INHIBITION OF P-GLYCOPROTEIN BY HIV PROTEASE INHIBITORS INCREASES INTRACELLULAR ACCUMULATION OF BERBERINE IN MURINE AND HUMAN MACROPHAGES.

Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages.

BackgroundHIV protease inhibitor (PI)-induced inflammatory response in macrophages is a major risk factor for cardiovascular diseases.We have previously reported that berberine (BBR), a traditional herbal medicine, prevents HIV Car Chargers PI-induced inflammatory response through inhibiting endoplasmic reticulum (ER) stress in macrophages.We also

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Integration of Postbiotics in Food Products through Attenuated Probiotics: A Case Study with Lactic Acid Bacteria in Bread

The study examines the integration of postbiotics in food products through the use of attenuated probiotics, specifically lactic acid bacteria (LAB) in bread.Postbiotics, non-viable microorganisms or their metabolites, offer health benefits similar to probiotics without the risks associated with live bacteria.This research evaluates the regulatory

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